Monday, January 21, 2019

Observing and Measuring Apoptosis


Many of the previously conducted research have tried to discover cell death, and also from the researches, it was discovered that apoptosis is considered the most understood outline of the average cell death. But up to now, some portions of this phenomenon were still remained mysterious.

However, the present research investigators slowed down a bit in the entire process, then the best idea of how the apoptosis would be really regulated in a body.

Ferrell together with his colleagues tried their theory in an egg cell of an African clawed frog, the Xenopus laevis. It has been performed by inducing apoptosis inside the cells, which has been extracted into a test tube, which were labeled by the green fluorescent protein.

The group observed that a green light, that became a pointer of the cell death, traveled throughout the test tube at a particular, constant speed.

How did the investigators identify the system by which the programmed cell death happened? They said, if the phenomenon takes place by diffusion, for example, the movement of a particle from the area of a high concentration to the lower concentration, it could have slowed down towards the end. However, since this is not the circumstances, the case concluded that a trigger wave — like a “spread of fire through the field” — might be the mechanism.

Reference:
Meghna Rao, Scientists Have Measured The “Speed Of Death” For The First Time Ever, 2019

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